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NEW YORK: A large protein found in spinach may aid in the development of new medications for millions around the world dealing with alcohol use disorders, chronic pain and mood disorders, researchers said.

The study, led by researchers from the Purdue University, discovered two peptides which are naturally metabolic products of Rubisco -- a large protein found in many plants like spinach -- that may aid in the development of new medications.

"These disorders are currently not adequately managed," said Richard van Rijn, Assistant Professor at Purdue.

"Better medications that take a more holistic approach and produce fewer side effects will be beneficial.

"We discovered that these peptides selectively activate the known beneficial pathways without activating the 'side-effect pathways' of the receptor," van Rijn added.

Right Nutrition, Mindful Eating: Key To Healthier, Happier You

Health Is The Key To Happiness

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By IANS The road to a happier you is right nutrition and mindful eating as well as staying away from too much of caffeine and sugar, suggests Rueben Ghosh, Co-Founder and Culinary Director at Yumlane and Kashmiri Barkakati, food expert at Momspresso. Here's how to do it right.

Legumes

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Consuming legumes will keep the blood sugar stable throughout the day, fostering happier mood, a key nutrient in creating a healthier gut.

Wraps

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Although a Western concept, wraps have surely found its popularity in India in the form of Frankie and rolled food items. The Kathi rolls are one example amongst the many variants and experiments with the delicacy in India. Consisting of various ingredients that could be included with the flatbread, chapatti or paratha like paneer, onions, green peas, ginger, garlic, mayonnaise or even mutton, a quick bite of this delicacy will appetize one's stomach and effectively boost one's mind into focusing on their work later.

Leafy Greens

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Leafy greens like spinach and Kale are extremely important in keeping brain functioning at its best with its Vitamin B. It produces Serotonin, a mood-enhancing chemical that helps lift our moods and keep depression at bay.

Whole Grains

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The discovery, published in the European Neuropsychopharmacolgy, aims to develop molecules that only activate the cellular signalling pathways associated with their therapeutic effect.

Preclinical studies suggest that the peptides are orally bioavailable and able to penetrate the blood-brain barrier, both of which are necessary for a drug to effectively treat a disorder of the central nervous system, van Rijn said.

The researchers are actively pursuing synthetic and computational strategies to improve these peptides to make them more effective.

The rubiscolin peptides are also being investigated for their ability to regulate dietary intake and are even commercially available in anti-ageing skin products.

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